Why Is Eliquis So Expensive?

Have you ever wondered why is Eliquis so expensive? Eliquis is expensive due to patent protection until 2026, lack of price regulations in the US, high R&D costs, and no generic alternatives.

What is Eliquis?

Eliquis (apixaban) is a prescription medication that helps prevent blood clots. It belongs to a group of medicines called direct oral anticoagulants (DOACs). Eliquis works by blocking a protein in the blood that causes clots to form.

Eliquis is approved for several uses, including:

• Treating and preventing deep vein thrombosis (DVT) and pulmonary embolism (PE).
• Preventing stroke and blood clots in people with nonvalvular atrial fibrillation.
• Preventing DVT and PE after hip or knee replacement surgery.

How Does Eliquis Work?

Blood clots form when a protein called fibrinogen is turned into fibrin strands, which trap blood cells to create a mesh that stops bleeding. Factor Xa is a key enzyme in this process, as it converts prothrombin into thrombin, which then changes fibrinogen into fibrin.

Eliquis works by blocking Factor Xa, reducing thrombin production and the formation of fibrin. While this action helps prevent dangerous blood clots

So… Why is Eliquis so Expensive?

Several factors contribute to the high cost of Eliquis:

Patent Protection

Research and Development Costs

The exact research and development (R&D) costs for Eliquis have not been disclosed. However, estimates suggest that bringing a new drug from discovery to market typically costs between $600 million and $2.6 billion. Despite these costs, Eliquis has generated revenue far beyond these figures.

For instance, Medicare spent $27.2 billion on Eliquis from 2016 to 2020—more than ten times the average R&D cost for a drug. This suggests that the high price of Eliquis is not primarily due to its development expenses but is influenced by the pharmaceutical industry’s pricing strategies and profit-driven approach.

Limited Competition

Eliquis is one of several direct oral anticoagulants, alongside alternatives like Xarelto (rivaroxaban) and Pradaxa (dabigatran). Despite the availability of these options, Eliquis is often positioned as a leading choice due to its efficacy and safety profile.

Clinical studies indicate that Eliquis is effective for preventing strokes and systemic embolism in patients with nonvalvular atrial fibrillation, as well as treating and preventing DVT and PE. These results have allowed its manufacturers to justify and maintain a high price, creating limited competition in the market.

Marketing and Distribution:

Promoting a drug like Eliquis to healthcare providers, insurance companies, and patients requires large amounts of money. This includes spending on advertising, sales teams, and educational campaigns to increase awareness and use of the drug.

Making sure the drug is widely available adds to the expenses. Costs for logistics, storage, and delivering the medication to pharmacies and hospitals all play a role in the overall price of Eliquis.

How Much Does Eliquis Cost in the US?

The price of Eliquis can vary depending on dosage, quantity, and where it is purchased. Factors like pharmacy location, insurance coverage, and supply size can all influence the overall cost.

Eliquis is available in 2.5 mg and 5 mg tablets. The prescribed dosage depends on the patient’s condition and treatment needs. Higher dosages or more frequent dosing can increase the total cost, making it more expensive for some patients.

The quantity purchased also affects pricing. 30-day supply is much more expensive than 90-day supply.

Prices for Eliquis can also differ between pharmacies. Chain pharmacies, independent stores, and online pharmacies may have different pricing. Online pharmacies, especially those based in Canada, often provide significant savings compared to U.S. pharmacies.

For those without insurance, Eliquis can be a major financial burden. A 30-day supply typically costs between $400 and $600, depending on dosage and quantity. This high price can make it difficult for patients to stay on their prescribed treatment.

Insurance coverage can lower the out-of-pocket cost for Eliquis. However, the final price depends on the specific plan, including copayments, deductibles, and whether Eliquis is covered on the insurer’s formulary. Some patients may pay as little as $10 to $50 for a 30-day supply, while others still face higher costs.

What is the Cheapest Way to Get Eliquis?

For patients looking to reduce their costs, here are some strategies:

1. 90-Day Supply: Purchasing a 90-day supply often reduces the cost per pill, offering savings compared to monthly refills.
2. Canadian Pharmacies: Some patients buy Eliquis reputable Canadian pharmacies, which may offer lower prices for the same medication. Ensure the Canadian pharmacy is licensed and trustworthy.
3. Coupons and Discounts: Look for coupons or discount cards from various sources, including online platforms and pharmacy programs, to help reduce out-of-pocket costs.

Final words

The high cost of Eliquis is a serious problem for many patients. Because it is protected by patents, there are no cheaper generic versions available, which allows the companies to charge very high prices—around $594 for just a month’s supply.

Many patients may struggle to pay for Eliquis, which could lead them to skip doses or not take it at all.