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Valdoxan (Agomelatine) Shopper Approved

Prescription Prescription Required FormationFormulation: Tablet

Valdoxan

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Prescription Prescription Required FormationFormulation: Tablet

Agomelatine

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Valdoxan (active ingredient: agomelatine) is a prescription medication indicated for:

  • Major Depressive Disorder (MDD): Valdoxan is used for the treatment of major depressive disorder in adults, helping to alleviate symptoms of depression and improve mood.

Valdoxan belongs to a class of drugs known as melatonergic antidepressants, which work by regulating circadian rhythms and balancing neurotransmitters in the brain to improve mood and relieve symptoms of depression.

Valdoxan (Agomelatine) comes in the form of a film-coated tablet and is taken orally. It may be taken with or without food, as advised by a doctor. Follow your doctor’s instructions regarding the use and dosage of Valdoxan. Treatment should not be started or should be stopped in patients with abnormal liver enzyme levels in the blood (more than three times the normal level).

The recommended dose is one tablet once a day, taken at bedtime. The usual recommended dose is one tablet of 25mg taken orally once daily, at bedtime. It may be taken with or without food. If there is no improvement in symptoms after two weeks, the doctor may increase the dose to two tablets taken together at bedtime. Patients with depression should be treated for at least six months to ensure they are free of symptoms.

Follow the instructions of your doctor regarding the use of Valdoxan, and to not take more or less of it than prescribed. Also, do not stop taking the medication abruptly without discussing it with your doctor first, as this may cause withdrawal symptoms.

Common Side Effects of Valdoxan (Agomelatine):

  • Abnormal dreams
  • Difficulty in sleeping (insomnia)
  • Dizziness
  • Headache
  • Inability to remain still
  • Migraine
  • Pins and needles in the fingers and toes
  • Restless legs syndrome
  • Sleepiness

Serious Side Effects of Valdoxan (Agomelatine):

  • Abnormal bleeding or bruising
  • Aggressive behavior
  • Agitation
  • Anxiety
  • Confusion
  • Hallucinations
  • Irritability
  • Itching, skin rash or hives
  • Nightmares
  • Restlessness
  • Shortness of breath, wheezing or trouble breathing
  • Suicidal thoughts or behaviour
  • Swelling of the face, lips, tongue, or other parts of the body
  • Yellow coloring of the skin or whites of the eyes (jaundice)

Valdoxan (Agomelatine) is available in the following forms and strength:

Valdoxan: Tablets

  • 25 mcg

  • Caution is advised when prescribing agomelatine to patients with liver disease or a history of liver disease, as the medication is metabolized in the liver.
  • Agomelatine should not be used in patients with severe kidney disease or end-stage renal failure, as there is limited information on the safety and effectiveness of the medication in this patient population.
  • There have been rare reports of hepatitis and elevated liver enzymes in patients taking agomelatine, so liver function tests should be performed before starting the medication and periodically during treatment.
  • Agomelatine should not be used in patients who are taking certain medications that can increase the risk of liver damage, such as ketoconazole or rifampicin.
  • Agomelatine can cause dizziness and somnolence, which can impair a patient’s ability to drive or operate machinery. Patients should be advised to avoid these activities until they know how the medication affects them.
  • There may be an increased risk of suicidal thoughts or behavior in some patients taking antidepressant medications, including agomelatine. Patients should be closely monitored, particularly when starting the medication or changing the dose.
  • Agomelatine should not be used in pregnancy unless the potential benefits outweigh the risks. The medication is excreted in breast milk, so caution should be exercised when prescribing it to nursing mothers.
  • Agomelatine should not be used in patients with a history of mania or hypomania, as it may induce these conditions in vulnerable patients.
  • Patients taking agomelatine should be advised to avoid alcohol, as it can increase the risk of side effects such as dizziness and sedation.
  • Agomelatine should be used with caution in patients with a history of epilepsy or seizures, as it may lower the seizure threshold.
  • There is limited information on the safety and effectiveness of agomelatine in elderly patients, so caution should be exercised when prescribing the medication to this population.
  • Agomelatine should be used with caution in patients with a history of bleeding disorders or those taking anticoagulant medications, as it may increase the risk of bleeding.
  • Patients taking agomelatine should be monitored for signs of serotonin syndrome, a potentially life-threatening condition that can occur when there is an excess of serotonin in the brain.
  • Agomelatine may interact with certain medications, so patients should inform their healthcare provider of all medications they are taking before starting the medication.

Can Valdoxan be used during pregnancy?

Valdoxan should be used with caution during pregnancy, and only if the potential benefits outweigh the risks to the fetus. Discuss any potential risks with a healthcare provider before taking the medication.

Is Valdoxan addictive?

Valdoxan is not believed to be addictive and does not have potential for abuse. However, as with all prescription medication, patients should follow their healthcare provider’s instructions on use and dosing.

Can Valdoxan be used with other medications?

Valdoxan may interact with certain medications, so patients should inform their healthcare provider of all medications they are taking before starting the medication. It should not be used in combination with medications that may increase the risk of liver damage.

REVIEWS

Additional Information Book
Generic name:

Agomelatine

Formulation:

Tablet

Strength(s):

25mg

Quantities Available:

28

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Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Valdoxan can I order at once from a Canadian pharmacy?

When ordering Valdoxan (agomelatine) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Valdoxan is commonly prescribed in a dosage of 25 mg, taken once daily in the evening. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day). If your prescription includes a higher dosage, such as 50 mg per day, taken as 25 mg twice daily, you would need to order 180 tablets (90 days x 2 tablets per day).

Do you sell agomelatine?

No, we do not sell agomelatine directly on our website. However, you can still enjoy low prices on Valdoxan, which contains agomelatine as an active ingredient. To purchase Valdoxan, you will need a valid prescription from your healthcare provider. We require this to dispense the medication safely and appropriately. You can submit your prescription by mailing it to us, faxing it, or uploading it through your online account.

Do you offer shipping of Valdoxan (agomelatine) to the United States?

Yes, we ship Valdoxan (agomelatine) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Valdoxan (Agomelatine). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Valdoxan (Agomelatine).