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Orgovyx (Relugolix) Shopper Approved

Prescription Prescription Required FormationFormulation: Controlled Release Tablet

Orgovyx

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Prescription Prescription Required FormationFormulation: Controlled Release Tablet

Relugolix

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Orgovyx (relugolix) is a prescription medication used for the treatment of advanced prostate cancer. It is an oral gonadotropin-releasing hormone (GnRH) receptor antagonist that works by reducing the production of testosterone, a hormone that fuels the growth of prostate cancer. Orgovyx is manufactured by Myovant Sciences, a biopharmaceutical company specializing in therapies for endocrine-related diseases.

Orgovyx is specifically indicated for treatment of adult patients with advanced prostate cancer: It is used to achieve medical castration by lowering testosterone levels, which is a key therapeutic strategy in managing advanced prostate cancer.

Orgovyx works as a GnRH receptor antagonist. By directly blocking the GnRH receptors in the pituitary gland, it rapidly reduces the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This leads to a significant decrease in testosterone production by the testes, achieving castration-level testosterone levels without the initial testosterone surge associated with GnRH agonists.

  • Initial dose: 360 mg orally on the first day
  • Maintenance dose: 120 mg orally once daily, starting on Day 2
  • Orgovyx should be taken at approximately the same time each day, with or without food.
  • Swallow tablets whole; do not crush or chew.

Orgovyx can cause side effects, ranging from mild to serious.

Common Side Effects:

  • Hot flushes (sudden feelings of warmth)​
  • Fatigue​
  • Muscle and joint pain
  • Diarrhea​
  • Constipation​
  • Weight gain​
  • Decreased sex drive​
  • Erectile dysfunction​
  • Increased blood sugar levels​
  • Increased blood fat (triglyceride) levels​
  • Decreased blood hemoglobin levels
  • Increased liver enzymes

These side effects were commonly reported in clinical trials.

Serious Side Effects:

  • Heart-related issues: Orgovyx can cause changes in the electrical activity of the heart (QT prolongation), which may lead to abnormal heart rhythms. Symptoms include dizziness, fainting, heart palpitations, and chest pain.​
  • Allergic reactions: Signs include swelling of the face, lips, tongue, or throat; trouble swallowing or breathing; and hives or rash.​
  • Sudden kidney injury: Symptoms include decreased urination, swelling in the legs or ankles, fatigue, and confusion.​
  • Severe bleeding: Unusual bruising, weakness, dizziness, low blood pressure, and confusion can be indicators.​

If you experience any serious side effects, contact your healthcare provider immediately.

Fertility Considerations:

Orgovyx may cause fertility problems in males, potentially affecting the ability to father children. Discuss any concerns regarding fertility with your healthcare provider before starting treatment.

Managing Side Effects:

If you experience side effects that are bothersome or do not go away, consult your doctor. They may provide strategies to manage these effects or adjust your treatment plan as necessary.​

Always inform your healthcare provider about all the medicines you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements, as these can interact with Orgovyx and affect how it works or cause side effects. ​

For a comprehensive list of side effects and more detailed information, refer to the prescribing information or consult your healthcare provider.

Orgovyx may cause changes in the heart’s electrical activity, leading to a condition known as QT interval prolongation. This can result in irregular heartbeats. Individuals with heart conditions, such as congenital long QT syndrome or heart failure, should be closely monitored during treatment. Regular electrocardiograms (ECGs) and electrolyte checks are recommended.

Some patients have experienced severe allergic reactions, including angioedema, characterized by swelling of the face, lips, tongue, or throat, leading to difficulty breathing or swallowing. If such symptoms occur, discontinue Orgovyx immediately and seek emergency medical attention.

Based on animal studies and its mechanism of action, Orgovyx can harm an unborn baby and may cause pregnancy loss if administered to a pregnant female. Males with female partners who can become pregnant should use effective contraception during treatment and for two weeks after the last dose.

Orgovyx can suppress the pituitary-gonadal system, potentially affecting diagnostic tests related to pituitary and gonadal functions. It’s important to monitor prostate-specific antigen (PSA) levels periodically during treatment.

Orgovyx can interact with various medications, potentially altering its effectiveness or increasing side effects. Inform your healthcare provider about all medications, supplements, and herbal products you are taking. Notably, certain drugs can increase the risk of side effects or reduce the effectiveness of Orgovyx.

While there are no known direct interactions between Orgovyx and alcohol, consuming alcohol during treatment may exacerbate certain side effects, such as diarrhea, hot flashes, and fatigue. Excessive alcohol consumption can lead to liver damage, and since Orgovyx may also affect liver function, it’s advisable to limit alcohol intake during treatment.

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Additional Information Book
Generic name:

Relugolix

Formulation:

Controlled Release Tablet

Strength(s):

120mg

Quantities Available:

30, 90

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

Can I buy Orgovyx from Canada?

Yes, you can purchase Orgovyx from Canada through Online Pharmacies Canada. Many customers choose our pharmacy due to the potential cost savings.

How much Orgovyx can I order at once from a Canadian pharmacy?

When ordering Orgovyx from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of chronic conditions without frequent refills.​

Dosage and Quantity:

  • Standard Dosage: Orgovyx is prescribed as a 120 mg tablet taken once daily.​

  • 90-Day Supply: To cover a 90-day period, you would require 90 tablets (1 tablet per day × 90 days).

Is it safe to buy Orgovyx from Canada?

Buying Orgovyx from Canada is safe if you order from a CIPA certified pharmacy. Online Pharmacies Canada is CIPA certified. Please contact our customer support if you have any questions about ordering Orgovyx from Canada.

Why is the cost of Orgovyx lower in Canada?

Orgovyx costs less in Canada because the government regulates drug prices. The Patented Medicine Prices Review Board (PMPRB) sets limits on how much manufacturers can charge, preventing high prices. In the U.S., pharmaceutical companies can set their own prices without restrictions, leading to higher costs.

Do you offer shipping of Orgovyx to the United States?

Yes, we ship Orgovyx to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Orgovyx (Relugolix). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Orgovyx (Relugolix).