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Exforge HCT (Amlodipine/Valsartan/Hydrochlorthiazide) Shopper Approved

Prescription Prescription Required FormationFormulation: Film Coated tablet

Exforge HCT

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Prescription Prescription Required FormationFormulation: Film Coated tablet

Amlodipine/Valsartan/Hydrochlorthiazide

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Exforge HCT is a prescription medication that combines three active ingredients: amlodipine, valsartan, and hydrochlorothiazide. It is used to treat high blood pressure (hypertension) in people who need all three medicines to help bring their blood pressure under better control.

Using three medications that work in different ways can provide a stronger blood pressure-lowering effect than using one or two medicines alone.

What is Hypertension?

Hypertension means the pressure of blood against the walls of the arteries remains too high over time.

High blood pressure often does not cause noticeable symptoms, but it can gradually damage the heart, blood vessels, kidneys, brain, and other organs if it is not properly controlled.

Keeping blood pressure within the range recommended by your healthcare provider can help reduce the risk of complications such as heart attack, stroke, and kidney problems.

How Amlodipine Works

Amlodipine belongs to a group of medications called calcium channel blockers (CCBs).

Calcium helps the muscles in blood vessel walls contract. Amlodipine reduces the movement of calcium into these muscle cells, allowing the blood vessels to relax and widen.

When the blood vessels are more open, blood can flow more easily and the pressure inside the arteries decreases.

How Valsartan Works

Valsartan belongs to a group of medications called angiotensin II receptor blockers (ARBs).

Angiotensin II is a natural substance in the body that causes blood vessels to tighten. Valsartan blocks the action of angiotensin II, helping the blood vessels remain more relaxed.

This reduces resistance to blood flow and helps lower blood pressure.

How Hydrochlorothiazide Works

Hydrochlorothiazide is a thiazide diuretic, sometimes called a water pill.

It works through the kidneys to increase the removal of sodium and water from the body through urine.

Reducing extra fluid in the bloodstream lowers the amount of pressure placed on the blood vessel walls and can help decrease blood pressure.

How the Three Ingredients Work Together

Exforge HCT lowers blood pressure in several ways at the same time.

Amlodipine helps relax and widen blood vessels, valsartan prevents blood vessels from tightening, and hydrochlorothiazide helps remove excess sodium and fluid from the body.

Because these medicines target different causes of high blood pressure, they can work together to provide more effective control.

Who May Be Prescribed Exforge HCT?

Exforge HCT may be prescribed when treatment with one or two blood pressure medicines does not provide enough control.

It may also be used in people who are already taking amlodipine, valsartan, and hydrochlorothiazide separately and can conveniently take the three medicines together in one tablet.

Your healthcare provider will decide whether this combination is appropriate based on your blood pressure, medical history, kidney function, other health conditions, and response to previous treatments.

Why Blood Pressure Control Matters

Uncontrolled high blood pressure forces the heart to work harder and puts continued stress on the arteries.

Over time, this can contribute to damage in important organs. Keeping blood pressure under control helps reduce this strain and supports better cardiovascular and kidney health.

What to Expect From Treatment

Exforge HCT begins lowering blood pressure after treatment starts, but the full effect may develop gradually.

Your healthcare provider may check your blood pressure regularly and may also monitor kidney function and electrolyte levels, especially because hydrochlorothiazide can affect fluid and mineral balance.

Take Exforge HCT Even if You Feel Well

High blood pressure often has no obvious symptoms. You may feel completely normal even when your blood pressure is too high.

For this reason, continue taking Exforge HCT exactly as prescribed even after your blood pressure improves.

What Exforge HCT Does Not Do

Exforge HCT helps control hypertension, but it does not permanently cure high blood pressure.

Blood pressure may rise again if treatment is stopped. Do not stop taking the medication or change your dose without speaking with your healthcare provider first.

Exforge HCT is taken by mouth as a film-coated tablet, usually once daily. You can take it with or without food.

Take the tablet exactly as prescribed by your healthcare provider. Swallow it with water and try to take it at the same time each day so it becomes part of your regular routine.

Best Time of Day to Take It

Exforge HCT contains hydrochlorothiazide, which is a diuretic or “water pill.” It helps your body remove extra sodium and water through urine.

Because this can make you urinate more often, many people find it easier to take Exforge HCT earlier in the day. Taking it too close to bedtime may cause you to wake up during the night to urinate.

Recommended Starting Dose

A commonly used starting dose of Exforge HCT is 5 mg/160 mg/12.5 mg once daily.

This tablet contains:

  • 5 mg of amlodipine
  • 160 mg of valsartan
  • 12.5 mg of hydrochlorothiazide

Your actual starting dose may be different depending on the blood pressure medicines you were taking before, your current blood pressure, and your overall health.

How Your Dose Is Chosen

Your healthcare provider will consider several factors before deciding which Exforge HCT strength is appropriate for you.

These may include your blood pressure readings, kidney function, liver function, previous blood pressure treatment, other medications, and any side effects you experience.

If you were already taking amlodipine, valsartan, and hydrochlorothiazide separately, your healthcare provider may choose an Exforge HCT strength that closely matches those doses.

Dose Adjustments

If your blood pressure remains too high, your healthcare provider may gradually increase your dose.

Dose changes are usually based on how well your blood pressure responds and whether you develop side effects such as dizziness, swelling, or changes in electrolyte levels.

Do not adjust the dose on your own.

Maximum Daily Dose

The maximum recommended dose of Exforge HCT is generally 10 mg/320 mg/25 mg once daily.

This provides the highest recommended daily amounts of amlodipine, valsartan, and hydrochlorothiazide in the combination tablet.

Taking more than prescribed may increase the risk of very low blood pressure, dizziness, dehydration, kidney problems, or changes in potassium and other electrolytes.

Take Exforge HCT Regularly

Exforge HCT works best when it is taken every day as prescribed.

Do not take it only when your blood pressure seems high or when you feel symptoms. High blood pressure often has no obvious symptoms, so regular treatment is important even when you feel completely well.

When to Expect Improvement

Exforge HCT starts lowering blood pressure after treatment begins, but the full effect of a particular dose may take up to about 2 weeks.

Your healthcare provider may wait for this response before deciding whether your dose needs to be changed.

Monitor Your Blood Pressure

Your healthcare provider may recommend checking your blood pressure regularly at home.

Keeping a record of your readings can help show how well Exforge HCT is working and whether your treatment needs adjustment.

Stay Hydrated

Because hydrochlorothiazide increases urine production, it can sometimes contribute to dehydration or changes in electrolyte levels.

Drink fluids as recommended by your healthcare provider, especially during hot weather, illness, vomiting, or diarrhea.

Contact your healthcare provider if you develop severe thirst, weakness, confusion, muscle cramps, or persistent dizziness.

Do Not Stop Taking It on Your Own

Continue taking Exforge HCT even when your blood pressure improves.

Stopping the medication without medical guidance can cause your blood pressure to rise again and increase the strain on your heart and blood vessels.

Getting the Best Results

For the best results, take Exforge HCT once daily at a consistent time, follow your prescribed dose, and attend regular follow-up appointments.

Combining the medication with any diet, exercise, weight management, or other lifestyle changes recommended by your healthcare provider can also help improve long-term blood pressure control.

Common Side Effects of Exforge HCT (Amlodipine/Valsartan/Hydrochlorthiazide):

Serious Side Effects of Exforge HCT (Amlodipine/Valsartan/Hydrochlorthiazide):

  • Blurred vision
  • Choking feeling
  • Confusion
  • Constipation
  • Cough
  • Eye pain
  • Feeling jittery
  • Feeling unsteady
  • Fluttering in your chest
  • Increased thirst or urination
  • Irregular heartbeats
  • Lightheadedness
  • Limp feeling
  • Little or no urination
  • Loss of coordination
  • Muscle cramps
  • Muscle weakness
  • Numbness or tingling
  • Seeing halos around lights
  • Severe weakness
  • Shortness of breath
  • Slurred speech
  • Swelling in your feet or ankles
  • Tiredness
  • Tunnel vision
  • Unusual skin rash
  • Vomiting

Exforge HCT (Amlodipine/Valsartan/Hydrochlorthiazide) is available in the following forms and strength:

Exforge HCT: Film-Coated Tablet

  • 5/160/12.5 mg
  • 10/320/25 mg

If You Miss a Dose

If you miss a dose of Exforge HCT, take it as soon as you remember.

If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.

Pregnancy and Breastfeeding

Exforge HCT should not be used during pregnancy, especially during the second and third trimesters, because valsartan can harm an unborn baby.

If you are pregnant, planning to become pregnant, or breastfeeding, talk to your healthcare provider before using Exforge HCT.

Liver, Kidney, and Electrolyte Problems

Tell your healthcare provider if you have liver disease, kidney disease, or an electrolyte imbalance before starting treatment.

Exforge HCT can affect kidney function and levels of minerals such as potassium and sodium, so blood tests may be needed during treatment.

Dizziness and Fainting

Exforge HCT may cause dizziness, lightheadedness, or fainting, especially when you first start treatment or after your dose is increased.

Stand up slowly from sitting or lying positions. Avoid driving or operating machinery until you know how the medication affects you.

Dehydration

Hydrochlorothiazide can increase urine production and may cause your body to lose too much water and salt.

Drink fluids as recommended by your healthcare provider. Contact them if you develop severe thirst, weakness, dry mouth, confusion, or persistent dizziness.

Allergic Reactions

Rarely, Exforge HCT can cause a serious allergic reaction.

Seek immediate medical attention if you develop a rash, severe itching, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Medication Interactions

Exforge HCT can interact with certain medications, including other blood pressure medicines, potassium-sparing diuretics, lithium, and medicines that affect kidney function or electrolyte levels.

Tell your healthcare provider about all prescription medicines, over-the-counter products, vitamins, and herbal supplements you take.

Medication Allergies

Before starting Exforge HCT, tell your healthcare provider if you have ever had an allergic reaction to amlodipine, valsartan, hydrochlorothiazide, or any other medication.

This information helps your healthcare provider determine whether Exforge HCT is safe for you.

Is Exforge HCT safe for everyone?

No. Exforge HCT may not be suitable for everyone. It should be avoided or used with extra caution in people with certain conditions, such as severe liver problems, severe kidney problems, anuria (inability to produce urine), or an allergy to amlodipine, valsartan, hydrochlorothiazide, or any other ingredient in the medication. Your healthcare provider will review your medical history before deciding whether Exforge HCT is appropriate for you.

How long does it take for Exforge HCT to start working?

Exforge HCT begins lowering blood pressure after treatment starts, but the full effect may take time. Many people may notice improved blood pressure control within 2 to 4 weeks, depending on the dose and their individual response.

Can Exforge HCT be crushed or split?

Exforge HCT tablets should generally be swallowed whole with water. Do not crush, chew, or split the tablet unless your healthcare provider or pharmacist specifically tells you it is safe to do so.

Is Exforge HCT addictive?

No. Exforge HCT is not addictive. However, you should not stop taking it suddenly without speaking with your healthcare provider because your blood pressure may rise again.

Can Exforge HCT cause high potassium levels?

Yes, changes in potassium levels can occur while taking Exforge HCT. Hydrochlorothiazide may sometimes cause low potassium levels, while valsartan may increase potassium levels in some people. Your healthcare provider may order blood tests to monitor your potassium and other electrolytes during treatment.

How often should my blood pressure be checked?

Your healthcare provider will decide how often your blood pressure should be checked based on your readings, dose, and overall health. You may need more frequent checks when you first start Exforge HCT or after your dose is changed. Home blood pressure monitoring may also be recommended.

What is the best time of day to take Exforge HCT?

Exforge HCT is often taken in the morning or earlier in the day. Because it contains hydrochlorothiazide, it may increase urination. Taking it too close to bedtime could cause you to wake up during the night to use the bathroom. Try to take your dose at about the same time each day and follow the schedule recommended by your healthcare provider.

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Additional Information Book
Generic name:

Amlodipine/Valsartan/Hydrochlorthiazide

Formulation:

Film Coated tablet

Strength(s):

5/160/12.5mg, 10/320/25mg

Quantities Available:

28, 84

Why customers love Online Pharmacies Canada

Our online Canadian Pharmacy is known for high standards of quality, safety, and efficiency when it comes to medications.

Our pharmacy offers lower prices on prescription drugs compared to traditional pharmacies.

How to Order

How much Exforge HCT can I order at once from a Canadian pharmacy?

When ordering Exforge HCT (amlodipine/valsartan/hydrochlorothiazide) from a Canadian pharmacy, you can typically purchase up to a 90-day supply at one time, which is common for prescription medications to ensure adequate management of conditions without frequent refills.

Here’s what you need to know:

Dosage and Quantity: Exforge HCT is commonly prescribed in various combinations, such as 5 mg/160 mg/12.5 mg or 10 mg/320 mg/25 mg (amlodipine/valsartan/hydrochlorothiazide), taken once daily. For a 90-day supply, this means you would order 90 tablets (90 days x 1 tablet per day).

Do you sell amlodipine/valsartan/hydrochlorothiazide?

No, we do not sell amlodipine/valsartan/hydrochlorothiazide directly. However, you can still enjoy low prices on Exforge HCT, which contains amlodipine/valsartan/hydrochlorothiazide as an active ingredient. You will need a valid prescription from your healthcare provider to purchase this medication. We require a prescription to dispense the medication, which you can mail, fax, or upload through your online account.

Do you offer shipping of Exforge HCT (amlodipine/valsartan/hydrochlorthiazide) to the United States?

Yes, we ship Exforge HCT (amlodipine/valsartan/hydrochlorthiazide) to both the United States and Puerto Rico.

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Online Pharmacies Canada has provided information from third parties intended to increase awareness and does not contain all the information about Exforge HCT (Amlodipine/Valsartan/Hydrochlorthiazide). Talk to your doctor or other qualified medical practitioners for medical attention or advice, or if you have any concerns about Exforge HCT (Amlodipine/Valsartan/Hydrochlorthiazide).