Can Arava Treat My Rheumatid Arthritis?

Arava is a pyrimidine synthesis inhibitor that is used in the treatment of rheumatoid arthritis. It reduces the pain, stiffness, inflammation, and swelling associated with this disease, improves physical function, and staves off the joint damage that ultimately results

While Arava helps improve symptoms of rheumatoid arthritis such as tenderness and joint swelling, unlike other symptom relievers that focus only on pain relief, Arava slows the advancement of joint damage caused by rheumatoid arthritis

Arava works by reversibly inhibiting the enzyme DHODH that is part of the autoimmune process contributing to the disease. Additionally, Arava is the only oral DMARD indicated to improve physical function.

Before using this medicine, tell your health care provider about any of the following: if you are pregnant, planning to become pregnant, or breastfeeding if you are taking any prescription or nonprescription medicine, if you are allergic to any component present in this medicine.

What Should I Know Before Taking Arava?

• Arava may interfere with your body’s ability to fight off infection.
• It can damage your liver or cause blood problems
• It has been known to cause rare but serious skin reactions
• It can also reduce your blood cell count.
• Arava is not recommended for children less than 18 years old.
• It may take 4 weeks or more to notice any improvement while taking Arava.

What Should I Tell My Doctor Before Using Arava?

• It is important to tell your doctor if you:
• Are taking blood thinners
• Have stomach problems
• Have peptic ulcers
• Have liver or kidney function impairment
• Have a heart problem

What Are the Side Effects?

Most severe: Allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), heartburn, diarrhea, constipation, nausea, flatulence, headache, weakness, fluid retention, flu-like symptoms

Most common: Anorexia, diarrhea, dyspepsia, gastroenteritis, abnormal liver enzymes, nausea, GI/abdominal pain, mouth ulcer, vomiting

Other: Bronchitis, increased cough, respiratory infection, pharyngitis, pneumonia, rhinitis, sinusitis, alopecia, eczema, pruritus, rash, dry skin

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