Pregnancy and breastfeeding: There is not enough reliable information to know if glucosamine sulphate, glucosamine hydrochloride, or N-acetyl glucosamine is safe to use when pregnant or breastfeeding. Stay on the safe side and avoid use.
Asthma: Glucosamine might make asthma worse. Until more is known, people with asthma should be cautious about taking products that contain glucosamine.
Diabetes: There used to be some concern that glucosamine might increase blood sugar levels. But most research shows that glucosamine does not increase blood sugar levels in people with diabetes.
Glaucoma: Glucosamine might increase the pressure inside the eye and could worsen glaucoma. If you have glaucoma, talk to your healthcare provider before taking glucosamine.
High cholesterol: There used to be some concern that glucosamine might increase cholesterol levels. But most research shows that glucosamine does not seem to increase cholesterol levels.
High blood pressure: There used to be some concern that glucosamine might increase blood pressure. But most research shows that glucosamine does not seem to increase blood pressure.
Shellfish allergy: Glucosamine is produced from the shells of shrimp, lobster, and crabs. If you have a shellfish allergy, talk to your healthcare provider before using glucosamine.
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